SCHEMBL30445724

CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	9/20	0.54

▸	FNTA	P49354	8/20	0.53

▸	FNTB	P49356	8/20	0.53

▸	BACE2	Q9Y5Z0	3/20	0.49

▸	NPY1R	P25929	1/20	0.49

▸	NPY2R	P49146	1/20	0.49

▸	NPY4R	P50391	1/20	0.49

▸	CTSD	P07339	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31591522	0.94	FNTA (0.53)	BACE1FNTAFNTBBACE2CTSD
SCHEMBL30445424	0.92	BACE1 (0.49)	BACE1FNTAFNTB
SCHEMBL30445400	0.89	NPY4R (0.53)	FNTAFNTBNPY1RNPY2RNPY4R
SCHEMBL31510397	0.88	BACE1 (0.60)	BACE1FNTAFNTBBACE2
SCHEMBL29590508	0.88	NPY4R (0.54)	BACE1NPY1RNPY2RNPY4R
SCHEMBL30445800	0.87	FNTA (0.56)	BACE1FNTAFNTBBACE2
SCHEMBL30445821	0.87	FNTA (0.56)	BACE1FNTAFNTBBACE2CTSD
SCHEMBL30445782	0.86	BACE1 (0.50)	BACE1BACE2NPY1RNPY2RNPY4R
SCHEMBL30465912	0.86	FNTA (0.62)	BACE1FNTAFNTBBACE2NPY1R
SCHEMBL31031460	0.86	NPY4R (0.54)	BACE1BACE2NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4192843-A1	PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF	Ospedale Pediatrico Bambino Gesù (IT)	2023-06-14	—	—	EP	claimed