SCHEMBL30445735

SCHEMBL30445735

CC(C)(C)OC(=O)N[C@@H](CC(=O)O)C(=O)OC1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 6/20 0.55
CTSS P25774 3/20 0.49
CTSK P43235 3/20 0.49
ITGB3 P05106 4/20 0.48
ITGA2B P08514 4/20 0.48
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.42
KLK7 P49862 1/20 0.41
KLK5 Q9Y337 1/20 0.41
EPHX1 P07099 2/20 0.40
CASP1 P29466 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351823 0.90 CACNA1B (0.67) CACNA1BCTSSCTSKITGB3ITGA2B
SCHEMBL30089915 0.87 CACNA1B (0.48) CACNA1BCTSSCTSKITGB3ITGA2B
SCHEMBL6842296 0.87 CACNA1B (0.48) CACNA1BCTSSCTSKITGB3ITGA2B
SCHEMBL28628007 0.86 CACNA1B (0.52) CACNA1BCTSSCTSKHDAC4HDAC1
SCHEMBL16469897 0.86 CACNA1B (0.52) CACNA1BCTSSCTSKHDAC4HDAC1
SCHEMBL16330581 0.86 CACNA1B (0.52) CACNA1BCTSSCTSKHDAC4HDAC1
SCHEMBL192185 0.86 CACNA1B (0.48) CACNA1BCTSSCTSKITGB3ITGA2B
SCHEMBL4233928 0.86 CACNA1B (0.48) CACNA1BCTSSCTSKITGB3ITGA2B
SCHEMBL376117 0.86 CACNA1B (0.48) CACNA1BCTSSCTSKITGB3ITGA2B
SCHEMBL16470235 0.85 CACNA1B (0.51) CACNA1BCTSSCTSKHDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143744-A Aromatic ester compound and application thereof 陈艳莉 2023-05-23 CN disclosed