SCHEMBL30445748

CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](CO)C(=O)N[C@@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	12/20	0.54

▸	FNTB	P49356	12/20	0.54

▸	BACE1	P56817	4/20	0.47

▸	NPY1R	P25929	1/20	0.46

▸	NPY2R	P49146	1/20	0.46

▸	NPY4R	P50391	1/20	0.46

▸	BACE2	Q9Y5Z0	1/20	0.46

▸	PGGT1B	P53609	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30445719	1.00	FNTA (0.54)	FNTAFNTBBACE1NPY1RNPY2R
SCHEMBL30446238	0.92	FNTA (0.57)	FNTAFNTBBACE1PGGT1B
SCHEMBL30445426	0.92	FNTA (0.56)	FNTAFNTBBACE1NPY1RNPY2R
SCHEMBL7069273	0.89	FNTA (0.64)	FNTAFNTBBACE1PGGT1B
SCHEMBL29596043	0.89	BACE1 (0.52)	BACE1NPY1RNPY2RNPY4RBACE2
SCHEMBL6810437	0.88	FNTA (0.63)	FNTAFNTBBACE1PGGT1B
SCHEMBL6810443	0.88	FNTA (0.63)	FNTAFNTBBACE1PGGT1B
SCHEMBL30445416	0.88	FNTA (0.50)	FNTAFNTBNPY1RNPY2RNPY4R
SCHEMBL30465912	0.87	FNTA (0.62)	FNTAFNTBBACE1NPY1RNPY2R
SCHEMBL30445800	0.85	FNTA (0.56)	FNTAFNTBBACE1BACE2PGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4192843-A1	PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF	Ospedale Pediatrico Bambino Gesù (IT)	2023-06-14	—	—	EP	disclosed