Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | TP53 | P04637 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239230 | 1.00 | MAPT (0.74) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL25239232 | 1.00 | MAPT (0.74) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL25217880 | 0.85 | TP53 (0.75) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL25209983 | 0.83 | MAPT (0.78) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL30445554 | 0.83 | MAPT (0.78) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL16384037 | 0.78 | TP53 (1.00) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL30445802 | 0.77 | MAPT (0.66) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL25232353 | 0.77 | MAPT (0.66) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL30445856 | 0.75 | MAPT (0.62) | MAPTTP53ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL25257561 | 0.75 | MAPT (0.62) | MAPTTP53ALDH1A1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | MAPT 781/4885TP53 821/4885ALDH1A1 2117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.