Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.54 |
| ▸ | TFPI | P10646 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 4/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | NPY2R | P49146 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445792 | 0.96 | TFPI (0.53) | BACE1BACE2TFPINPY4RNPY1R | |
| SCHEMBL30445730 | 0.95 | BACE1 (0.53) | BACE1BACE2TFPINPY4RNPY1R | |
| SCHEMBL30445846 | 0.94 | BACE1 (0.60) | BACE1BACE2NPY4RNPY1RNPY2R | |
| SCHEMBL30445421 | 0.88 | NTSR2 (0.55) | BACE1BACE2NPY4RNPY1RNPY2R | |
| SCHEMBL30262130 | 0.87 | TFPI (0.57) | BACE1BACE2TFPIOPRM1OPRD1 | |
| SCHEMBL30445824 | 0.85 | NTSR2 (0.56) | BACE1BACE2NPY4RNPY1RNPY2R | |
| SCHEMBL30578763 | 0.85 | NPY4R (0.59) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30578759 | 0.85 | NPY4R (0.59) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30430659 | 0.84 | BACE1 (0.60) | BACE1BACE2TFPIOPRD1 | |
| SCHEMBL31319513 | 0.84 | TFPI (0.59) | TFPIOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | disclosed |