Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 18/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 10/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 7/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23784392 | 1.00 | EHMT2 (0.48) | EHMT2EHMT1DNMT1NSD2 | |
| SCHEMBL23784372 | 0.86 | EHMT2 (0.48) | EHMT2EHMT1DNMT1NSD2 | |
| SCHEMBL20581132 | 0.86 | EHMT2 (0.47) | EHMT2EHMT1DNMT1NSD2 | |
| Trifluoroacetic Acid SCHEMBL20581322 | 0.80 | EHMT2 (0.45) | EHMT2EHMT1DNMT1NSD2 | |
| SCHEMBL20581827 | 0.75 | EHMT2 (0.48) | EHMT2EHMT1DNMT1 | |
| SCHEMBL20580549 | 0.74 | EHMT2 (0.49) | EHMT2EHMT1DNMT1 | |
| SCHEMBL23784361 | 0.71 | EHMT2 (0.57) | EHMT2EHMT1 | |
| SCHEMBL23029678 | 0.71 | EHMT2 (0.71) | EHMT2EHMT1DNMT1NSD2 | |
| Hydrochloric Acid SCHEMBL20581014 | 0.71 | EHMT2 (0.56) | EHMT2EHMT1 | |
| SCHEMBL20581091 | 0.70 | EHMT2 (0.53) | EHMT2EHMT1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634962-B1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-05-24 | — | — | EP | disclosed |