SCHEMBL30449130

SCHEMBL30449130

CCOc1ccccc1-c1cc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc(-c2ccccc2OCC)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 2/20 0.56
ENPP3 O14638 1/20 0.56
PTPRC P08575 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
DHFR P00374 1/20 0.42
SYK P43405 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
PDE3A Q14432 1/20 0.40
GRM5 P41594 1/20 0.40
PIP4K2A P48426 1/20 0.39
MAPT P10636 1/20 0.39
PDE10A Q9Y233 1/20 0.39
LTB4R Q15722 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NR3C1 P04150 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21670585 1.00 ENPP1 (0.56) ENPP1ENPP3PTPRCADORA3DHFR
SCHEMBL30525966 1.00 ENPP1 (0.56) ENPP1ENPP3PTPRCADORA3DHFR
SCHEMBL21670563 1.00 ENPP1 (0.56) ENPP1ENPP3PTPRCADORA3DHFR
SCHEMBL29430001 0.87 ENPP1 (0.46) ENPP1ENPP3PTPRCDHFRMAOA
SCHEMBL967279 0.87 ENPP1 (0.46) ENPP1ENPP3PTPRCDHFRMAOA
SCHEMBL6266961 0.87 HSP90AA1 (0.48) ENPP1ENPP3ADORA3KDM4EALDH1A1
SCHEMBL30525970 0.87 HSP90AA1 (0.48) ENPP1ENPP3ADORA3KDM4EALDH1A1
SCHEMBL21670579 0.86 ENPP1 (0.42) ENPP1ENPP3PTPRCDHFRMAOA
SCHEMBL21670556 0.86 ENPP1 (0.42) ENPP1ENPP3PTPRCDHFRMAOA
SCHEMBL30525971 0.86 ENPP1 (0.42) ENPP1ENPP3PTPRCDHFRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115869867-B Microcapsule containing polyurethane/urea resin wall material of siloxane and preparation method thereof 湖南大学 2023-09-19 CN disclosed
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed
CN-115869867-A Microcapsule containing polyurethane/urea resin wall material of siloxane and preparation method thereof 湖南大学 2023-03-31 CN disclosed