Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 18/20 | 0.61 |
| ▸ | CDK2 | P24941 | 18/20 | 0.61 |
| ▸ | CDK1 | P06493 | 13/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 13/20 | 0.61 |
| ▸ | CCND1 | P24385 | 12/20 | 0.61 |
| ▸ | CDK6 | Q00534 | 12/20 | 0.61 |
| ▸ | CDK4 | P11802 | 11/20 | 0.61 |
| ▸ | CCND3 | P30281 | 11/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.52 |
| ▸ | CDK7 | P50613 | 5/20 | 0.52 |
| ▸ | CDK9 | P50750 | 5/20 | 0.52 |
| ▸ | CCNH | P51946 | 5/20 | 0.52 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977093 | 1.00 | CCNE1 (0.61) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977479 | 0.92 | CCNE1 (0.59) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL30449433 | 0.91 | CDK2 (0.71) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977426 | 0.91 | CDK2 (0.71) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977281 | 0.90 | CCNE1 (0.60) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL30449838 | 0.90 | CCNE1 (0.60) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977461 | 0.90 | CCNE1 (0.72) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29820976 | 0.90 | CCNE1 (0.72) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22976918 | 0.88 | CCNE1 (0.60) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977173 | 0.88 | CCNE1 (0.59) | CCNE1CDK2CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | disclosed |