Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.60 |
| ▸ | CDK2 | P24941 | 19/20 | 0.60 |
| ▸ | CDK1 | P06493 | 14/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 14/20 | 0.57 |
| ▸ | CCND1 | P24385 | 12/20 | 0.57 |
| ▸ | CDK6 | Q00534 | 12/20 | 0.57 |
| ▸ | CDK4 | P11802 | 10/20 | 0.57 |
| ▸ | CCND3 | P30281 | 10/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.56 |
| ▸ | CDK7 | P50613 | 4/20 | 0.56 |
| ▸ | CDK9 | P50750 | 4/20 | 0.56 |
| ▸ | CCNH | P51946 | 4/20 | 0.56 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977466 | 1.00 | CCNE1 (0.60) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977340 | 0.93 | CCNE1 (0.63) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL30449696 | 0.93 | CCNE1 (0.63) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL30449728 | 0.90 | CCNE1 (0.57) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977425 | 0.90 | CCNE1 (0.57) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977484 | 0.89 | CCNE1 (0.61) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29820665 | 0.89 | CCNE1 (0.58) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977235 | 0.89 | CCNE1 (0.60) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL22977044 | 0.89 | CCNE1 (0.58) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29821495 | 0.89 | CCNE1 (0.60) | CCNE1CDK2CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | disclosed |