Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.55 |
| ▸ | CDK2 | P24941 | 19/20 | 0.55 |
| ▸ | CCND1 | P24385 | 13/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 13/20 | 0.53 |
| ▸ | CDK1 | P06493 | 12/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.53 |
| ▸ | CDK4 | P11802 | 11/20 | 0.53 |
| ▸ | CCND3 | P30281 | 11/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.50 |
| ▸ | CDK9 | P50750 | 6/20 | 0.50 |
| ▸ | CDK7 | P50613 | 5/20 | 0.50 |
| ▸ | CCNH | P51946 | 5/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977195 | 1.00 | CCNE1 (0.55) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30449724 | 0.93 | CCNE1 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977236 | 0.93 | CCNE1 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977235 | 0.91 | CCNE1 (0.60) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL29821495 | 0.91 | CCNE1 (0.60) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977345 | 0.91 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30449311 | 0.91 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22977488 | 0.90 | CCNE1 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL22976996 | 0.90 | CCNE1 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL23001302 | 0.88 | CCNE1 (0.42) | CCNE1CDK2CCND1CDK6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | disclosed |