Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.86 |
| ▸ | GAK | O14976 | 1/20 | 0.86 |
| ▸ | LCK | P06239 | 1/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.86 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.86 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.86 |
| ▸ | EPHA5 | P54756 | 1/20 | 0.86 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059878 | 1.00 | MAPK14 (0.86) | MAPK14GAKLCKCYP3A4PDGFRB | |
| Ro-3201195 SCHEMBL6157573 | 0.93 | MAPK14 (1.00) | MAPK14GAKLCKCYP3A4PDGFRB | |
| Ro-3201195 SCHEMBL4108597 | 0.93 | MAPK14 (1.00) | MAPK14GAKLCKCYP3A4PDGFRB | |
| Ro-3201195 SCHEMBL29437792 | 0.93 | MAPK14 (1.00) | MAPK14GAKLCKCYP3A4PDGFRB | |
| Ro-3201195 SCHEMBL1417312 | 0.93 | MAPK14 (1.00) | MAPK14GAKLCKCYP3A4PDGFRB | |
| Ro-3201195 SCHEMBL31046797 | 0.93 | MAPK14 (1.00) | MAPK14GAKLCKCYP3A4PDGFRB | |
| SCHEMBL6160174 | 0.86 | MAPK14 (0.75) | MAPK14GAKLCKCYP3A4PDGFRB | |
| SCHEMBL18722103 | 0.86 | MAPK14 (0.81) | MAPK14GAKLCKCYP3A4PDGFRB | |
| SCHEMBL2356260 | 0.85 | MAPK14 (0.74) | MAPK14GAKLCKCYP3A4PDGFRB | |
| SCHEMBL2356231 | 0.84 | MAPK14 (0.76) | MAPK14GAKLCKCYP3A4PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3069732-B1 | DRUG FOR TREATING CORNEAL ENDOTHELIUM BY PROMOTING CELL PROLIFERATION OR INHIBITING CELL DAMAGE | THE DOSHISHA (JP) | 2023-07-12 | — | — | EP | disclosed |