Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147068 | 1.00 | IDO1 (0.49) | IDO1CYP11B1CYP11B2POLBALDH1A1 | |
| SCHEMBL30448914 | 1.00 | IDO1 (0.49) | IDO1CYP11B1CYP11B2POLBALDH1A1 | |
| SCHEMBL147069 | 1.00 | IDO1 (0.49) | IDO1CYP11B1CYP11B2POLBALDH1A1 | |
| SCHEMBL145967 | 0.95 | IDO1 (0.44) | IDO1CYP11B1CYP11B2POLBALDH1A1 | |
| SCHEMBL145968 | 0.95 | IDO1 (0.44) | IDO1CYP11B1CYP11B2POLBALDH1A1 | |
| SCHEMBL20198880 | 0.93 | IDO1 (0.47) | IDO1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29978733 | 0.91 | IDO1 (0.49) | IDO1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL147127 | 0.91 | IDO1 (0.49) | IDO1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL147126 | 0.91 | IDO1 (0.49) | IDO1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20198881 | 0.90 | IDO1 (0.46) | IDO1ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139857-B | Sulfoximine, sulfoximinamide, sulfodiimine, and diimine sulfonamide compounds as indoleamine 2,3-dioxygenase inhibitors | 重庆复尚源创医药技术有限公司 | 2023-07-21 | — | — | CN | disclosed |