Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 9/20 | 0.49 |
| ▸ | CCNH | P51946 | 9/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.49 |
| ▸ | CCNK | O75909 | 13/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 13/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.48 |
| ▸ | CDK2 | P24941 | 11/20 | 0.48 |
| ▸ | CDK9 | P50750 | 11/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977257 | 1.00 | CDK7 (0.49) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL22997848 | 0.86 | CDK7 (0.43) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL22977399 | 0.86 | CCNE1 (0.57) | CDK7CCNHMNAT1CCNT1CCNE1 | |
| SCHEMBL22977029 | 0.86 | CCNE1 (0.50) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL29821092 | 0.86 | CCNE1 (0.50) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL22977423 | 0.86 | CCNK (0.45) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL22977402 | 0.82 | CCNE1 (0.47) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL22977403 | 0.82 | CDK7 (0.51) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL22977338 | 0.82 | CCNK (0.46) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL30449196 | 0.82 | CDK7 (0.51) | CDK7CCNHMNAT1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | disclosed |