Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20509884 | 1.00 | TP53 (0.44) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL19973584 | 0.94 | KMT2A (0.46) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL19973585 | 0.94 | KMT2A (0.46) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL20511808 | 0.88 | TP53 (0.49) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL26597540 | 0.87 | TP53 (0.48) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL19973612 | 0.83 | TRPV1 (0.44) | TP53RAB9ANPC1SMN1; SMN2AKR1C3 | |
| SCHEMBL19973902 | 0.83 | TRPV1 (0.44) | TP53RAB9ANPC1SMN1; SMN2AKR1C3 | |
| SCHEMBL20511799 | 0.82 | CYP1A2 (0.42) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL26597461 | 0.82 | CYP1A2 (0.42) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL19973509 | 0.82 | TP53 (0.47) | TP53RAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472063-A | Targeted conjugates comprising modified siRNAs | 阿布特斯生物制药公司 | 2023-07-21 | — | — | CN | disclosed |