Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | FES | P07332 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032719 | 1.00 | ABL1 (0.57) | ABL1HDAC6CFDERN1JAK2 | |
| SCHEMBL29032794 | 0.94 | ABL1 (0.57) | ABL1HDAC6CFDMMP2MMP9 | |
| SCHEMBL29032789 | 0.92 | ABL1 (0.55) | ABL1HDAC6MMP2MMP9MMP8 | |
| SCHEMBL30450644 | 0.92 | ABL1 (0.55) | ABL1HDAC6MMP2MMP9MMP8 | |
| SCHEMBL29032783 | 0.92 | ABL1 (0.56) | ABL1HDAC6CFDERN1JAK2 | |
| SCHEMBL29032702 | 0.92 | ABL1 (0.59) | ABL1HDAC6MAP4K4PRKCGROCK1 | |
| SCHEMBL30451514 | 0.92 | ABL1 (0.56) | ABL1HDAC6CFDERN1JAK2 | |
| SCHEMBL29032704 | 0.92 | ABL1 (0.59) | ABL1HDAC6EPHX2NR1H4LMNA | |
| SCHEMBL30450526 | 0.92 | ABL1 (0.59) | ABL1HDAC6MAP4K4PRKCGROCK1 | |
| SCHEMBL29032788 | 0.90 | ABL1 (0.58) | ABL1HDAC6CFDERN1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | claimed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | claimed |
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |