Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | CYBB | P04839 | 1/20 | 0.34 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588186 | 0.80 | BACE1 (0.56) | BACE1METAP2PIM1PIM2PTPN5 | |
| SCHEMBL12895889 | 0.75 | BACE1 (0.52) | BACE1METAP2PIM1PIM2PTPN5 | |
| SCHEMBL12895896 | 0.75 | BACE1 (0.52) | BACE1METAP2PIM1PIM2PTPN5 | |
| SCHEMBL30985267 | 0.71 | PTPN1 (0.59) | BACE1METAP2ALDH1A1KDM4ETSHR | |
| SCHEMBL1538767 | 0.71 | PTPN1 (0.59) | BACE1METAP2ALDH1A1KDM4ETSHR | |
| SCHEMBL12320899 | 0.71 | BACE1 (0.48) | BACE1METAP2PIM1PIM2PTPN5 | |
| SCHEMBL12310186 | 0.71 | BACE1 (0.48) | BACE1METAP2PIM1PIM2PTPN5 | |
| SCHEMBL12473661 | 0.71 | BACE1 (0.48) | BACE1METAP2PIM1PIM2PTPN5 | |
| SCHEMBL30706974 | 0.71 | PTPN1 (0.59) | BACE1METAP2ALDH1A1KDM4ETSHR | |
| SCHEMBL9804973 | 0.70 | PTPN1 (0.52) | BACE1METAP2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261456-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-06-13 | — | — | CN | disclosed |