Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114623 | 0.95 | LCK (0.50) | LCKPDPK1DYRK1AKMT2AP2RX3 | |
| SCHEMBL25300411 | 0.95 | LCK (0.50) | LCKPDPK1DYRK1AKMT2AP2RX3 | |
| SCHEMBL30450749 | 0.88 | DYRK1A (0.49) | LCKDYRK1ANPC1RAB9A | |
| SCHEMBL30450350 | 0.85 | LCK (0.51) | LCKPDPK1DYRK1AKMT2AEPHX2 | |
| SCHEMBL31114633 | 0.84 | DYRK1A (0.51) | LCKDYRK1A | |
| SCHEMBL25303404 | 0.84 | DYRK1A (0.51) | LCKDYRK1A | |
| SCHEMBL25303187 | 0.82 | DYRK1A (0.54) | LCKDYRK1AKMT2AMEN1 | |
| SCHEMBL30450170 | 0.82 | DYRK1A (0.54) | LCKDYRK1AKMT2AMEN1 | |
| SCHEMBL25304187 | 0.82 | AXL (0.57) | PIK3CAEPHX2NPC1RAB9A | |
| SCHEMBL30450473 | 0.82 | AXL (0.57) | PIK3CAEPHX2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460500-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |