Claziprotamide

Claziprotamide

SCHEMBL30451828

O=C(Cc1ccc(C2CC2)c(F)c1)N1CCN(c2ccc(Cl)nn2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PANK3 Q9H999 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Claziprotamide SCHEMBL22609127 1.00 PANK3 (1.00) PANK3
SCHEMBL26501361 0.88 PANK3 (0.78) PANK3
SCHEMBL22920478 0.88 PANK3 (1.00) PANK3
SCHEMBL22489433 0.86 PANK3 (0.75) PANK3
SCHEMBL23054468 0.85 PANK3 (0.75) PANK3
SCHEMBL23054440 0.85 PANK3 (0.75) PANK3
SCHEMBL22609119 0.85 PANK3 (1.00) PANK3
SCHEMBL23040152 0.85 PANK3 (1.00) PANK3
SCHEMBL22920473 0.85 PANK3 (1.00) PANK3
SCHEMBL22920471 0.85 PANK3 (1.00) PANK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025227071-A1 METHODS AND COMPOSITIONS FOR TREATING HEART FAILURE AND LIVER DISEASE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-10-30 WO claimed
WO-2025227071-A1 METHODS AND COMPOSITIONS FOR TREATING HEART FAILURE AND LIVER DISEASE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-10-30 WO disclosed
CN-111818922-B Small molecule modulators of pantothenate kinase 圣朱德儿童研究医院有限公司 2023-06-13 CN disclosed