SCHEMBL30451960

SCHEMBL30451960

O=P(O)(Cl)OOc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.50
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
ACP3 P15309 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GPR84 Q9NQS5 1/20 0.37
MMP2 P08253 1/20 0.37
MMP8 P22894 1/20 0.37
MMP14 P50281 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
MAPT P10636 1/20 0.37
PTK2B Q14289 1/20 0.37
TSHR P16473 1/20 0.36
ANPEP P15144 1/20 0.36
LAP3 P28838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3065840 0.82 SRC (0.43) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL3401427 0.82 SRC (0.60) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL3490037 0.82 SRC (0.54) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL9856545 0.82 SRC (0.43) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL2065936 0.81 MEN1 (0.45) CYP2C19CA2MMP2MMP8MMP14
Hydrochloric Acid SCHEMBL3065842 0.80 SRC (0.52) SRCCYP2C9CYP2C19CA2CA4
Methyl Alcohol SCHEMBL29038483 0.78 SRC (0.50) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL56862 0.77 SRC (0.67) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL11122924 0.77 SRC (0.48) SRCCYP2C9CYP2C19CA2CA4
SCHEMBL28441444 0.77 SRC (0.59) SRCCYP2C9CYP2C19TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111989335-B Phosphonamide ester compounds and salts thereof and related crystalline forms, methods of preparation and uses 四川科伦博泰生物医药股份有限公司 2023-06-13 CN disclosed