Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 15/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432494 | 1.00 | RET (0.55) | RETCCNE1CDK2 | |
| SCHEMBL28429908 | 0.88 | RET (0.66) | RETCCNE1CDK2 | |
| SCHEMBL30452005 | 0.88 | RET (0.66) | RETCCNE1CDK2 | |
| SCHEMBL28434212 | 0.85 | RET (0.55) | RETCCNE1CDK2 | |
| SCHEMBL28432516 | 0.84 | RET (0.62) | RETCCNE1CDK2 | |
| SCHEMBL28430448 | 0.80 | RET (0.55) | RETCCNE1CDK2 | |
| SCHEMBL28440184 | 0.80 | RET (0.58) | RET | |
| SCHEMBL28438511 | 0.79 | RET (0.55) | RET | |
| SCHEMBL28430460 | 0.79 | RET (0.53) | RETCCNE1CDK2 | |
| SCHEMBL28437649 | 0.79 | RET (0.56) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |