SCHEMBL30452085

SCHEMBL30452085

COc1cc(CCO)c(Cl)cc1Br

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 12/20 0.49
TAAR1 Q96RJ0 4/20 0.49
HTR2C P28335 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24252862 1.00 HTR2A (0.49) HTR2ATAAR1HTR2C
SCHEMBL30467763 0.86 HTR2A (0.47) HTR2ATAAR1HTR2C
SCHEMBL24252762 0.86 HTR2A (0.47) HTR2ATAAR1HTR2C
SCHEMBL29733616 0.84 HTR2A (0.68) HTR2ATAAR1HTR2C
SCHEMBL1145570 0.84 HTR2A (0.68) HTR2ATAAR1HTR2C
SCHEMBL3220881 0.79 PDE4A (0.46) HTR2ATAAR1HTR2C
SCHEMBL30451569 0.79 HTR2A (0.47) HTR2ATAAR1HTR2C
SCHEMBL24252452 0.79 HTR2A (0.47) HTR2ATAAR1HTR2C
SCHEMBL7165538 0.78 SMN1; SMN2 (0.53) HTR2ATAAR1HTR2C
SCHEMBL31063345 0.76 HTR2A (0.54) HTR2ATAAR1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 CN disclosed