SCHEMBL30452392

SCHEMBL30452392

Fc1cc2ccnnc2cc1Br

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.32
IDO1 P14902 1/20 0.30
PIK3R1 P27986 1/20 0.30
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20265531 0.73 HTT (0.53)
SCHEMBL22324050 0.73 PDGFRB (0.42)
SCHEMBL30008594 0.69 BACE1 (0.48) PIK3R1PIK3CA
SCHEMBL30467720 0.69 HTT (0.53) PIK3R1PIK3CA
SCHEMBL4536243 0.69 HTT (0.53) PIK3R1PIK3CA
SCHEMBL19014027 0.69 KDM4E (0.39) PIK3CA
SCHEMBL1543520 0.69 BACE1 (0.48) PIK3R1PIK3CA
SCHEMBL31083024 0.69
SCHEMBL13739182 0.69 CYP1A2 (0.48)
SCHEMBL31457732 0.69 AXL (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 CN disclosed