Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.47 |
| ▸ | GNA15 | P30679 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204830 | 0.89 | FFAR1 (0.47) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL3008775 | 0.88 | FFAR1 (0.62) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL2690136 | 0.87 | FFAR1 (0.55) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL14344065 | 0.85 | FFAR1 (0.51) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL203274 | 0.80 | FFAR1 (0.56) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL206778 | 0.78 | FFAR1 (0.71) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL765390 | 0.78 | FFAR1 (0.71) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL205213 | 0.77 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL2690535 | 0.77 | FFAR1 (0.63) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL15397937 | 0.75 | FFAR1 (0.60) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248812-B1 | FUSED CYCLIC COMPOUNDS AS GPR40 RECEPTOR MODULATORS | TAKEDA PHARMACEUTICAL (JP) | 2013-12-25 | — | — | EP | disclosed |
| EP-2248812-A2 | Fused cyclic compounds as GPR40 receptor modulators | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |