Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23828924 | 1.00 | NAMPT (0.52) | NAMPTDPP8DPP9 | |
| SCHEMBL23840728 | 0.89 | HPGD (0.51) | NAMPT | |
| SCHEMBL23828880 | 0.83 | NAMPT (0.52) | NAMPT | |
| SCHEMBL31646737 | 0.80 | NAMPT (0.52) | NAMPTDPP8DPP9 | |
| SCHEMBL23828891 | 0.78 | NAMPT (0.57) | NAMPT | |
| SCHEMBL30453424 | 0.78 | NAMPT (0.57) | NAMPT | |
| SCHEMBL27923200 | 0.73 | DPP8 (0.57) | NAMPTDPP8DPP9 | |
| SCHEMBL29992618 | 0.72 | DPP8 (0.55) | NAMPTDPP8DPP9 | |
| SCHEMBL8203594 | 0.72 | DPP8 (0.55) | NAMPTDPP8DPP9 | |
| SCHEMBL3438648 | 0.70 | NOTUM (0.61) | NAMPTDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164084-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-23 | — | — | CN | disclosed |