Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 10/20 | 0.54 |
| ▸ | SRC | P12931 | 10/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 6/20 | 0.47 |
| ▸ | FYN | P06241 | 6/20 | 0.47 |
| ▸ | YES1 | P07947 | 6/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016222 | 0.96 | CDK2 (0.58) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2115487 | 0.87 | AKT2 (0.65) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2115490 | 0.87 | AKT2 (0.65) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2117358 | 0.81 | KDR (0.55) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL31672436 | 0.81 | KDR (0.55) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2117364 | 0.81 | KDR (0.55) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2114522 | 0.81 | CDK2 (0.56) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2114520 | 0.81 | CDK2 (0.56) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2118199 | 0.80 | CDK2 (0.51) | CDK2KDRSRCAKT2FGFR1 | |
| SCHEMBL2118195 | 0.80 | CDK2 (0.51) | CDK2KDRSRCAKT2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |