Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405306 | 0.83 | KMT2A (0.40) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL31405280 | 0.83 | TDP1 (0.48) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL29196759 | 0.81 | POLB (0.44) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL30453552 | 0.81 | KMT2A (0.38) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL29196758 | 0.81 | TDP1 (0.41) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL29196775 | 0.79 | HTT (0.46) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL28424154 | 0.79 | TOP2A (0.49) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL30454149 | 0.79 | POLB (0.47) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL29196757 | 0.78 | HDAC6 (0.46) | TDP1KMT2ATP53MEN1HPGD | |
| SCHEMBL29196769 | 0.78 | POLB (0.43) | TDP1KMT2ATP53MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283765-A | Chlorotrifluoromethylation method of inactive olefin | 苏州大学 | 2023-06-23 | — | — | CN | disclosed |