Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.70 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.67 |
| ▸ | RET | P07949 | 5/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.67 |
| ▸ | FLT3 | P36888 | 5/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.67 |
| ▸ | ABL1 | P00519 | 2/20 | 0.67 |
| ▸ | FLT1 | P17948 | 5/20 | 0.63 |
| ▸ | AURKA | O14965 | 4/20 | 0.63 |
| ▸ | CSF1R | P07333 | 3/20 | 0.63 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.63 |
| ▸ | FLT4 | P35916 | 3/20 | 0.63 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.63 |
| ▸ | STK3 | Q13188 | 3/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.63 |
| ▸ | SRC | P12931 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.63 |
| ▸ | PLK4 | O00444 | 2/20 | 0.63 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113961 | 1.00 | KDR (0.70) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL2113963 | 1.00 | KDR (0.70) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL24192106 | 0.87 | PDPK1 (0.67) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL2114263 | 0.86 | RET (0.65) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL24192389 | 0.86 | KDR (0.53) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL30454169 | 0.86 | RET (0.65) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL2114264 | 0.86 | RET (0.65) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL2118577 | 0.85 | KDR (0.70) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL30454095 | 0.85 | KDR (0.70) | KDRALKRETFGFR1FLT3 | |
| SCHEMBL2118582 | 0.85 | KDR (0.70) | KDRALKRETFGFR1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |