Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 7/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | FAM20C | Q8IXL6 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588511 | 1.00 | TNNI3K (0.49) | TNNI3KKDRBRD4FAM20CIGF1R | |
| SCHEMBL590349 | 0.91 | KDR (0.49) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL30454194 | 0.91 | KDR (0.49) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL1116469 | 0.90 | KDR (0.46) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL31672486 | 0.90 | KDR (0.46) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL1116463 | 0.87 | KDR (0.44) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL31672403 | 0.87 | KDR (0.44) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL31672509 | 0.83 | KDR (0.41) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL10151182 | 0.83 | KDR (0.41) | KDRBRD4FAM20CIGF1REGFR | |
| SCHEMBL589264 | 0.83 | KDR (0.46) | TNNI3KKDRIGF1RBRAFAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |