SCHEMBL30453090

SCHEMBL30453090

COc1cccc(CCc2cc(OC)c(OC)c(OC)c2O)c1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 15/20 0.58
ABCG2 Q9UNQ0 3/20 0.53
HTR1A P08908 3/20 0.52
DRD2 P14416 3/20 0.52
TAAR1 Q96RJ0 1/20 0.49
GABRA1 P14867 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28816467 0.92 ABCB1 (0.58) ABCB1ABCG2HTR1ADRD2TAAR1
SCHEMBL29229173 0.92 ABCB1 (0.56) ABCB1ABCG2HTR1ADRD2TAAR1
SCHEMBL30080126 0.84 TAAR1 (0.54) ABCB1ABCG2HTR1ADRD2TAAR1
SCHEMBL29066047 0.81 CYP4F2 (0.56) ABCB1
Methyl Alcohol SCHEMBL7428563 0.80 ABCB1 (0.74) ABCB1ABCG2HTR1ADRD2
SCHEMBL7438145 0.80 ABCB1 (0.78) ABCB1ABCG2HTR1ADRD2
SCHEMBL7437650 0.80 ABCB1 (0.60) ABCB1ABCG2HTR1ADRD2TAAR1
SCHEMBL7448046 0.78 ABCB1 (0.57) ABCB1ABCG2HTR1ADRD2TAAR1
Hydrochloric Acid SCHEMBL7434492 0.77 TAAR1 (0.69) ABCB1ABCG2HTR1ADRD2TAAR1
SCHEMBL29079537 0.77 AKR1B1 (0.62) ABCB1HTR1ADRD2TAAR1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116162080-B Extraction method and application of bibenzyl compound 沈阳药科大学 2024-12-06 CN disclosed
CN-116162080-A Extraction method and application of bibenzyl compound 沈阳药科大学 2023-05-26 CN disclosed