Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | KDR | P35968 | 10/20 | 0.59 |
| ▸ | SRC | P12931 | 14/20 | 0.57 |
| ▸ | LCK | P06239 | 8/20 | 0.54 |
| ▸ | FYN | P06241 | 8/20 | 0.54 |
| ▸ | YES1 | P07947 | 8/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405110 | 0.85 | CDK2 (0.57) | PDPK1CDK2KDRSRCLCK | |
| SCHEMBL5365048 | 0.84 | RET (0.67) | PDPK1CDK2KDRSRCLCK | |
| SCHEMBL5369843 | 0.81 | SRC (0.59) | CDK2KDRSRCLCKFYN | |
| SCHEMBL7138258 | 0.81 | MEN1 (0.66) | CDK2KDRSRCLCKFYN | |
| SCHEMBL5728095 | 0.81 | PDPK1 (0.73) | PDPK1CDK2KDRSRCLCK | |
| SCHEMBL5363321 | 0.81 | PDPK1 (0.73) | PDPK1CDK2KDRSRCLCK | |
| SCHEMBL7136883 | 0.80 | SRC (0.58) | CDK2KDRSRCLCKFYN | |
| SCHEMBL5361470 | 0.80 | SRC (0.63) | CDK2KDRSRCLCKFYN | |
| SCHEMBL5373623 | 0.80 | SRC (0.55) | CDK2KDRSRCLCKFYN | |
| SCHEMBL5361428 | 0.80 | LRRK2 (0.64) | CDK2KDRSRCLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |