Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 12/20 | 0.50 |
| ▸ | PARP1 | P09874 | 9/20 | 0.50 |
| ▸ | FLT1 | P17948 | 3/20 | 0.49 |
| ▸ | FLT4 | P35916 | 3/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589341 | 1.00 | HDAC1 (0.53) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL30452921 | 0.90 | KDR (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL588547 | 0.90 | KDR (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL30452644 | 0.85 | KDR (0.61) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL588581 | 0.85 | KDR (0.61) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL31672478 | 0.83 | KDR (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL10151205 | 0.83 | KDR (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL589306 | 0.82 | KDR (0.53) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL589388 | 0.82 | KDR (0.66) | LCKJAK3KDRPARP1FLT1 | |
| SCHEMBL30452580 | 0.82 | KDR (0.66) | LCKJAK3KDRPARP1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |