Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.49 |
| ▸ | VEGFA | P15692 | 3/20 | 0.40 |
| ▸ | FLT1 | P17948 | 3/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257796 | 0.93 | EGLN1 (0.47) | EGLN1MIFGRM5GRM1S1PR1 | |
| SCHEMBL24257559 | 0.91 | EGLN1 (0.59) | EGLN1MIF | |
| SCHEMBL24257715 | 0.83 | EGLN1 (0.53) | EGLN1 | |
| SCHEMBL24257555 | 0.82 | EGLN1 (0.66) | EGLN1 | |
| SCHEMBL24257767 | 0.77 | NPC1 (0.41) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257606 | 0.76 | EGLN1 (0.48) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257842 | 0.75 | EGLN1 (0.52) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257554 | 0.74 | EGLN1 (0.48) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257716 | 0.71 | EGLN1 (0.58) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL30546836 | 0.71 | EGLN1 (0.58) | EGLN1VEGFAFLT1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |