Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396685 | 1.00 | CA1 (0.58) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL13853068 | 0.94 | CA1 (0.48) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL29550379 | 0.91 | CA1 (0.61) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL3204645 | 0.91 | CA1 (0.61) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL3098313 | 0.90 | KDM4E (0.49) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL16383357 | 0.89 | CA1 (0.63) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL12841581 | 0.87 | CA9 (0.50) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL29947213 | 0.87 | CA12 (0.64) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL14725053 | 0.87 | CA12 (0.64) | CA1CA9CA12KDM4EALDH1A1 | |
| SCHEMBL29758957 | 0.87 | CA12 (0.64) | CA1CA9CA12KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049078-A1 | DIFLUORO- AND TRIFLUORO-ACETYL HYDRAZIDES AS SELECTIVE HDAC6 INHIBITORS | ITALFARMACO SPA (IT) | 2026-02-19 | — | — | US | disclosed |
| EP-4558494-A1 | 1,3,4-OXADIAZOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | ITALFARMACO S.p.A. (IT) | 2025-05-28 | — | — | EP | disclosed |
| US-20250059139-A1 | COMPOUNDS FOR TREATMENT OF CANCER | THE JOHNS HOPKINS UNIVERSITY | 2025-02-20 | — | — | US | disclosed |
| EP-4452946-A2 | COMPOUNDS FOR TREATMENT OF CANCER | The Johns Hopkins University (US) | 2024-10-30 | — | — | EP | disclosed |
| EP-3152190-B1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC (US) | 2024-07-31 | — | — | EP | disclosed |
| WO-2024017897-A1 | 1,3,4-OXADIAZOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | ITALFARMACO S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |
| US-20230286970-A1 | NOVEL OXADIAZOLE-BASED SELECTIVE HDAC6 INHIBITORS | ITALFARMACO SPA (IT) | 2023-09-14 | — | — | US | disclosed |
| WO-2023122612-A2 | COMPOUNDS FOR TREATMENT OF CANCER | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286970-A1 | NOVEL OXADIAZOLE-BASED SELECTIVE HDAC6 INHIBITORS | HDAC6, HDAC1, HDAC3 | CA1 2006/4885CA9 3614/4885CA12 3023/4885 |
| US-20260049078-A1 | DIFLUORO- AND TRIFLUORO-ACETYL HYDRAZIDES AS SELECTIVE HDAC6 INHIBITORS | HDAC3, HDAC1, HDAC6 | CA1 200/4885CA9 253/4885CA12 460/4885 |
| US-20250059139-A1 | COMPOUNDS FOR TREATMENT OF CANCER | KLK3, ACP3, TP53 | CA1 1895/4885CA9 152/4885CA12 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.