Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 7/20 | 0.48 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.48 |
| ▸ | MTOR | P42345 | 11/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25359834 | 1.00 | ATR (0.48) | ATRATRIPMTORLRRK2PDE4D | |
| SCHEMBL25359841 | 1.00 | ATR (0.48) | ATRATRIPMTORLRRK2PDE4D | |
| SCHEMBL30454261 | 0.86 | MTOR (0.53) | ATRATRIPMTOR | |
| SCHEMBL30455141 | 0.86 | MTOR (0.53) | ATRATRIPMTOR | |
| SCHEMBL25285572 | 0.86 | MTOR (0.53) | ATRATRIPMTOR | |
| SCHEMBL25353363 | 0.86 | MTOR (0.53) | ATRATRIPMTOR | |
| SCHEMBL25353367 | 0.86 | MTOR (0.53) | ATRATRIPMTOR | |
| SCHEMBL30454213 | 0.79 | CYP1A2 (0.49) | ATRATRIPLRRK2 | |
| SCHEMBL25355866 | 0.79 | CYP1A2 (0.49) | ATRATRIPLRRK2 | |
| SCHEMBL25353561 | 0.78 | MTOR (0.44) | ATRATRIPMTORLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |