Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 1.00 |
| ▸ | ABL1 | P00519 | 17/20 | 1.00 |
| ▸ | ABL2 | P42684 | 14/20 | 1.00 |
| ▸ | BCR | P11274 | 4/20 | 0.74 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | STK25 | O00506 | 1/20 | 0.60 |
| ▸ | CIT | O14578 | 1/20 | 0.60 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.60 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | CASK | O14936 | 1/20 | 0.60 |
| ▸ | GAK | O14976 | 1/20 | 0.60 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.60 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.60 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657933 | 1.00 | SRC (1.00) | SRCABL1ABL2BCRKDR | |
| SCHEMBL6183059 | 0.92 | SRC (0.85) | SRCABL1ABL2BCRKDR | |
| SCHEMBL1657913 | 0.91 | SRC (1.00) | SRCABL1ABL2BCRKDR | |
| SCHEMBL30453979 | 0.91 | SRC (1.00) | SRCABL1ABL2BCRKDR | |
| SCHEMBL3152315 | 0.91 | SRC (0.83) | SRCABL1ABL2BCRKDR | |
| SCHEMBL28565311 | 0.89 | SRC (0.88) | SRCABL1ABL2BCRKDR | |
| SCHEMBL676581 | 0.89 | SRC (1.00) | SRCABL1ABL2BCRKCNH2 | |
| SCHEMBL30453888 | 0.89 | SRC (1.00) | SRCABL1ABL2BCRKCNH2 | |
| SCHEMBL1657788 | 0.88 | SRC (1.00) | SRCABL1ABL2BCRFYN | |
| SCHEMBL30453073 | 0.88 | SRC (1.00) | SRCABL1ABL2BCRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |