Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332257 | 1.00 | HTR2C (0.50) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| SCHEMBL20139214 | 1.00 | HTR2C (0.50) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| SCHEMBL20139212 | 1.00 | HTR2C (0.50) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL20141132 | 0.98 | HTR2C (0.51) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL7326909 | 0.98 | HTR2C (0.51) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL20141129 | 0.98 | HTR2C (0.51) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL11553326 | 0.98 | HTR2C (0.51) | HTR2CKDM1AHTR2AHTR2BTAAR1 | |
| Bicarbonate SCHEMBL11624938 | 0.92 | HTR2C (0.44) | HTR2CKDM1AHTR2AHTR2BDDB1 | |
| SCHEMBL27529265 | 0.86 | HTR2C (0.53) | HTR2CHTR2AHTR2BCA1CA2 | |
| Hydrochloric Acid SCHEMBL27666727 | 0.84 | HTR2C (0.54) | HTR2CHTR2AHTR2BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121713-A1 | BCL-2 INHIBITORS | NEW AVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |