Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198319 | 0.85 | TSHR (0.56) | TSHRLMNADNM1 | |
| SCHEMBL366647 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL4745188 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL15211724 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL12844942 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL24044418 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL13601912 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL985792 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL13475536 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 | |
| SCHEMBL14848213 | 0.85 | TSHR (0.46) | TSHRLMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171279-A | Macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-116171279-A | Macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2023-05-26 | — | — | CN | disclosed |