Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 20/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25290857 | 1.00 | KHK (0.65) | KHKPDE10A | |
| SCHEMBL25245366 | 1.00 | KHK (0.65) | KHKPDE10A | |
| SCHEMBL30456022 | 0.87 | KHK (0.60) | KHKPDE10A | |
| SCHEMBL30954225 | 0.87 | KHK (0.60) | KHKPDE10A | |
| SCHEMBL31212736 | 0.86 | KHK (0.53) | KHKPDE10A | |
| SCHEMBL25771044 | 0.86 | KHK (0.53) | KHKPDE10A | |
| SCHEMBL30567283 | 0.85 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL29030930 | 0.85 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL29030897 | 0.85 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL25289909 | 0.85 | KHK (0.57) | KHKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118414332-A | (S) -2- (2-methylazetidin-1-yl) pyrimidine derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-07-30 | — | — | CN | claimed |
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | claimed |
| CN-118414332-A | (S) -2- (2-methylazetidin-1-yl) pyrimidine derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-07-30 | — | — | CN | disclosed |
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |