Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.78 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.78 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.78 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.78 |
| ▸ | MAP4K4 | O95819 | 10/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Aminoquinazoline SCHEMBL31377585 | 0.88 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL142513 | 0.88 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL29363315 | 0.88 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL2521546 | 0.86 | PI4KA (0.95) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL29723576 | 0.86 | PI4KA (0.95) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL29618413 | 0.86 | PI4KA (0.95) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL29631400 | 0.86 | PI4KA (0.95) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL4171913 | 0.86 | PI4KA (0.95) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL28400783 | 0.81 | PI4KA (0.78) | PI4KAPI4K2BPI4K2API4KBMAP4K4 | |
| 4-Aminoquinazoline SCHEMBL29481714 | 0.80 | PI4KA (0.68) | PI4KAPI4K2BPI4K2API4KBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |