Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 15/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 10/20 | 0.51 |
| ▸ | CCND1 | P24385 | 6/20 | 0.51 |
| ▸ | CCND3 | P30281 | 4/20 | 0.51 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 2/20 | 0.43 |
| ▸ | CLK3 | P49761 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | DYRK4 | Q9NR20 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 9/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309541 | 0.86 | CDK4 (0.51) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL22172304 | 0.86 | CDK4 (0.51) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL30818384 | 0.82 | CDK4 (0.55) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL16892106 | 0.82 | CDK4 (0.55) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL19209875 | 0.82 | CDK4 (0.39) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL29402856 | 0.82 | CDK4 (0.55) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL28487809 | 0.76 | CDK4 (0.56) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL19966562 | 0.76 | IRAK4 (0.39) | CDK4RPS6KA3KDREGFRHTR2A | |
| SCHEMBL29402884 | 0.76 | CDK4 (0.57) | CDK4HDAC1CDK6CCND1CCND3 | |
| SCHEMBL19968025 | 0.76 | CDK4 (0.57) | CDK4HDAC1CDK6CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157847-A1 | DRUG-LIKE MOLECULES AND METHODS FOR THE THERAPEUTIC TARGETING OF VIRAL RNA STRUCTURES | University of Washington (US) | 2023-04-05 | — | — | EP | disclosed |