Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226777 | 1.00 | MEN1 (0.48) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL31501644 | 1.00 | MEN1 (0.48) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL25270741 | 1.00 | MEN1 (0.48) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL25270732 | 0.93 | MEN1 (0.47) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL31501642 | 0.93 | MEN1 (0.47) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL25270731 | 0.93 | MEN1 (0.47) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL30456088 | 0.93 | MEN1 (0.47) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL31501630 | 0.92 | MEN1 (0.53) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL31501632 | 0.92 | MEN1 (0.48) | MEN1KMT2AKCNH2KITDRD2 | |
| SCHEMBL25226883 | 0.92 | MEN1 (0.48) | MEN1KMT2AKCNH2KITDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444313-A1 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |