Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223159 | 1.00 | MEN1 (0.40) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL25272420 | 1.00 | MEN1 (0.40) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL31501631 | 0.95 | MEN1 (0.43) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL30405361 | 0.88 | MEN1 (0.45) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL31501637 | 0.88 | MEN1 (0.45) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL25277615 | 0.88 | MEN1 (0.45) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL25277616 | 0.88 | MEN1 (0.45) | MEN1CNR1DRD2HTR2ADRD3 | |
| SCHEMBL30456045 | 0.86 | MEN1 (0.46) | MEN1KMT2AEGFRKDR | |
| SCHEMBL25271281 | 0.86 | MEN1 (0.46) | MEN1KMT2AEGFRKDR | |
| SCHEMBL25227044 | 0.83 | MEN1 (0.51) | MEN1CNR1DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444313-A1 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |