Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.49 |
| ▸ | CDK2 | P24941 | 15/20 | 0.49 |
| ▸ | CDK9 | P50750 | 15/20 | 0.49 |
| ▸ | CDK7 | P50613 | 12/20 | 0.49 |
| ▸ | CCNH | P51946 | 12/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363678 | 1.00 | CCNK (0.49) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL31220711 | 0.92 | CCNK (0.51) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25363014 | 0.92 | CCNK (0.51) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL31220745 | 0.91 | CCNK (0.51) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25360542 | 0.91 | CCNK (0.51) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25363261 | 0.91 | CCNK (0.50) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL31220678 | 0.91 | CCNK (0.50) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL31220649 | 0.91 | CCNK (0.47) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL31220662 | 0.89 | CCNK (0.50) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25363464 | 0.89 | CCNK (0.50) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4455132-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | Insilico Medicine IP Limited (HK) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023116761-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 英矽智能科技知识产权有限公司 | 2023-06-29 | — | — | WO | disclosed |