Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 17/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25227448 | 1.00 | CHRM5 (0.57) | CHRM5CYP3A4CYP2D6NAMPT | |
| SCHEMBL25231206 | 0.90 | CHRM5 (0.53) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL30456656 | 0.82 | CHRM5 (0.78) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL25231101 | 0.82 | CHRM5 (0.78) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL25275612 | 0.81 | CHRM5 (0.54) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL30457331 | 0.81 | CHRM5 (0.54) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL25279334 | 0.80 | CHRM5 (0.73) | CHRM5CYP3A4 | |
| SCHEMBL25276383 | 0.80 | CHRM5 (0.70) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL25231654 | 0.80 | CHRM5 (0.58) | CHRM5CYP3A4CYP2D6 | |
| SCHEMBL25280620 | 0.78 | CHRM5 (0.70) | CHRM5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | CHRM5, CHRM1, CHRM2 | CHRM5 1/4885CYP3A4 520/4885CYP2D6 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.