Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 19/20 | 0.51 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24088713 | 1.00 | CTPS1 (0.51) | CTPS1CTPS2MKNK1MKNK2 | |
| SCHEMBL22490802 | 0.85 | CTPS1 (0.70) | CTPS1CTPS2 | |
| SCHEMBL21044431 | 0.82 | CTPS1 (0.74) | CTPS1CTPS2 | |
| SCHEMBL22490838 | 0.82 | CTPS1 (0.56) | CTPS1CTPS2 | |
| SCHEMBL22490818 | 0.81 | CTPS1 (0.48) | CTPS1CTPS2 | |
| SCHEMBL30455611 | 0.81 | CTPS1 (0.48) | CTPS1CTPS2 | |
| SCHEMBL22490771 | 0.81 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL22490816 | 0.81 | CTPS1 (0.60) | CTPS1CTPS2 | |
| SCHEMBL22490786 | 0.80 | CTPS1 (0.54) | CTPS1CTPS2 | |
| SCHEMBL22490775 | 0.79 | CTPS1 (0.54) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717465-B1 | COMPOUNDS | STEP PHARMA S A S (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-12319680-B2 | Compounds | STEP PHARMA S.A.S. (FR) | 2025-06-03 | — | — | US | disclosed |
| US-20230183229-A1 | Compounds | SYGNATURE DISCOVERY LIMITED (GB) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183229-A1 | Compounds | UGT1A1, CYP1A1, CYP1B1 | CTPS1 2556/4885CTPS2 2833/4885MKNK1 2780/4885 |
| US-12319680-B2 | Compounds | UGT1A1, CYP1A1, CYP1B1 | CTPS1 2556/4885CTPS2 2833/4885MKNK1 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.