Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 17/20 | 0.72 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.72 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.72 |
| ▸ | CDK2 | P24941 | 11/20 | 0.72 |
| ▸ | CDK9 | P50750 | 11/20 | 0.72 |
| ▸ | CDK7 | P50613 | 11/20 | 0.53 |
| ▸ | CCNH | P51946 | 11/20 | 0.53 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25364470 | 1.00 | CCNK (0.72) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL26046133 | 0.88 | CCNK (0.83) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30204070 | 0.83 | CCNK (1.00) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24588737 | 0.83 | CCNK (1.00) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24839545 | 0.83 | CCNK (1.00) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30456179 | 0.81 | CCNK (0.63) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30456603 | 0.81 | CCNK (0.69) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24588779 | 0.81 | CCNK (0.48) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30457179 | 0.81 | CCNK (0.60) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24588258 | 0.80 | CDK7 (0.73) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647607-A | Pyrimidine heterocyclic compounds, process for preparing the same and pharmaceutical use thereof | 英矽智能科技(上海)有限公司 | 2024-09-13 | — | — | CN | disclosed |
| WO-2023116761-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 英矽智能科技知识产权有限公司 | 2023-06-29 | — | — | WO | disclosed |