Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245392 | 1.00 | MIF (0.41) | MIFMAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL25284635 | 0.87 | MIF (0.42) | MIFMAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL30362219 | 0.78 | MIF (0.38) | MIFMAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL26135768 | 0.78 | MIF (0.38) | MIFMAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL30457766 | 0.77 | CFTR (0.38) | MIFMAPK1SMN1; SMN2KDM4EPDE4B | |
| SCHEMBL25230754 | 0.77 | CFTR (0.38) | MIFMAPK1SMN1; SMN2KDM4EPDE4B | |
| SCHEMBL25280795 | 0.77 | MIF (0.37) | MIFMAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL30362103 | 0.77 | MIF (0.37) | MIFMAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL25277492 | 0.76 | PDE4B (0.47) | PDE4BKMT2ASTSMEN1PKM | |
| SCHEMBL26543564 | 0.76 | MIF (0.36) | MIFMAPK1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448508-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114823-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |