Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3522896 | 1.00 | KCNN4 (0.47) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL3522893 | 1.00 | KCNN4 (0.47) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL3527440 | 0.78 | KCNN4 (0.43) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL3522115 | 0.76 | KCNN4 (0.52) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL27183395 | 0.76 | KCNN4 (0.57) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL1871740 | 0.71 | KCNN4 (0.47) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL6369689 | 0.69 | KCNN4 (0.57) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL30114522 | 0.69 | CYP3A4 (0.60) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL2131459 | 0.69 | CYP3A4 (0.60) | KCNN4HTR2AHTR2COPRK1KCNH2 | |
| SCHEMBL8157067 | 0.68 | KCNN4 (0.61) | KCNN4HTR2AHTR2COPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4181908-A2 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | Adimabio LLC (US) | 2023-05-24 | — | — | EP | claimed |