SCHEMBL30457044

SCHEMBL30457044

C=CC(=O)OCCCOc1ccc(C#Cc2ccc(C(=O)Oc3ccc(OC(=O)c4ccc(C#Cc5ccc(OCCCOC(=O)C=C)cc5)cc4)c(C(=O)OCCCCCCCCCCOc4ccc(-c5ccc(C#N)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
MMP3 P08254 6/20 0.38
MMP2 P08253 5/20 0.37
PTPN2 P17706 4/20 0.35
PTPN1 P18031 3/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP13 P45452 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
HTT P42858 1/20 0.35
PTPN11 Q06124 2/20 0.34
PTPN6 P29350 1/20 0.34
THRB P10828 1/20 0.34
HRH2 P25021 1/20 0.34
HRH1 P35367 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25276683 1.00 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL30456612 0.99 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL30457662 0.99 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL25227956 0.99 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL25226273 0.99 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL30457539 0.99 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL25269639 0.99 HDAC1 (0.40) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL4335911 0.97 HDAC1 (0.42) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL496334 0.97 HDAC1 (0.42) HDAC1HDAC2MMP3MMP2PTPN2
SCHEMBL29459219 0.97 HDAC1 (0.42) HDAC1HDAC2MMP3MMP2PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444822-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2024-10-16 EP disclosed
WO-2023104545-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2023-06-15 WO disclosed