Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374981 | 0.97 | DPP4 (0.41) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL31376809 | 0.96 | DPP4 (0.40) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL24961034 | 0.94 | DPP4 (0.36) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL25281235 | 0.94 | DPP4 (0.36) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL24691272 | 0.94 | DPP4 (0.36) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL30002339 | 0.93 | DPP4 (0.36) | DPP4DPP7DPP8DPP9FAP | |
| Trifluoroacetic Acid SCHEMBL25270519 | 0.93 | DPP4 (0.36) | DPP4DPP7CTSVCTSLCTSB | |
| Trifluoroacetic Acid SCHEMBL32664813 | 0.89 | DPP4 (0.41) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL31375006 | 0.88 | DPP4 (0.33) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL31376782 | 0.87 | DPP4 (0.33) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059171-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-02-20 | — | — | US | disclosed |
| EP-4444711-A1 | ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023104882-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059171-A1 | ANTIVIRAL COMPOUNDS | ZC3HAV1, ACE, EIF2AK2 | DPP4 8/4885DPP7 37/4885DPP8 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.